《植物生理学报》

植物中α-酮戊二酸/Fe(II)依赖双加氧酶研究进展

王熙昂，王彪，李海燕，邢巧娟，赵鹏斌，顾馨怡，李宏博^*

沈阳农业大学园艺学院, 沈阳110866

通信作者：李宏博；E-mail: lhb@syau.edu.cn

摘　要：

α-酮戊二酸(2OG)/Fe(II)依赖双加氧酶(2-oxoglutarate/ Fe(II)-dependent dioxygenases, 2-ODD)广泛参与植物的多种代谢过程, 是植物体内一种重要的氧化酶。它不仅对植物的生长发育具有重要意义, 而且在许多药用植物活性成分的生物合成中扮演重要的角色。本文主要综述2-ODD参与的不同代谢反应, 为深入研究2-ODD功能提供参考。

关键词：α-酮戊二酸/Fe(II)依赖双加氧酶; 氧化酶; 羟基化; 去甲基化; 生物合成

收稿：2021-05-11   修定：2021-07-31

资助：2018年全国中药资源普查项目(1102-01042918001)和中央本级重大增减支项目“名贵中药资源可持续利用能力建设” (2060302)

Research progress of 2-oxoglutarate/Fe(ii)-dependent dioxygenases in plant

WANG Xi’ang, WANG Biao, LI Haiyan, XING Qiaojuan, ZHAO Pengbin, GU Xinyi, LI Hongbo^*

College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning 110866, China

Corresponding author: LI Hongbo; E-mail: lhb@syau.edu.cn

Abstract:

2-oxoglutarate/Fe(II)-dependent dioxygenases is a critical kind of oxygenase in plant, which are widely involved in various metabolic pathway of plant. Not only can they regulate growth and development of almost all kinds of plants, but they also play an important role in the biosynthesis pathway of active in-gredients of herbs. In this review, metabolic reactions catalyzed by 2-ODD were described. Consequently, this will provide references for future study of 2-ODD. 

Key words: 2-oxoglutarate/Fe(II)-dependent dioxygenases; oxygenase; hydroxylation; demethylation; bio-synthesis